Scarlett E. Lee

Jul 21, 2023 | medscape.com | Scarlett E. Lee |Sharon Greene |Cara C. Burns |Graham F. Tallis

Abstract and Introduction Introduction Since the World Health Assembly established the Global Polio Eradication Initiative (GPEI) in 1988, two of the three wild poliovirus (WPV) serotypes (types 2 and 3) have been eradicated, and global WPV cases have decreased by more than 99.9%. Afghanistan and Pakistan remain the only countries where indigenous WPV type 1 (WPV1) transmission has not been interrupted.

May 11, 2023 | cdc.gov | Scarlett E. Lee

Poliovirus VaccinationIn April 2016, trivalent OPV (tOPV), consisting of Sabin strain types 1, 2, and 3, was withdrawn from routine immunization programs and supplementary immunization activities (SIAs)* worldwide and replaced with bivalent OPV (bOPV, containing Sabin-strain types 1 and 3). Routine immunization programs worldwide provide either 3 doses of bOPV and 1–2 doses of injectable inactivated poliovirus vaccine (IPV) or IPV alone.