Scott France

2 months ago | dx.doi.org | Scott France |Erick A. Lindsey |Emma L. McInturff |Simon Berritt

2 months ago | pubs.acs.org | Scott France |Erick A. Lindsey |Emma L. McInturff |Simon Berritt

Dec 18, 2023 | dx.doi.org | Scott France |Erick A. Lindsey |Emma L. McInturff |Simon Berritt

Dec 18, 2023 | pubs.acs.org | Scott France |Emma L. McInturff |Simon Berritt |Erick A. Lindsey

In 2022, 23 new small molecule chemical entities were approved as drugs by the United States FDA, European Union EMA, Japan PMDA, and China NMPA. This review describes the synthetic approach demonstrated on largest scale for each new drug based on patent or primary literature. The synthetic routes highlight practical methods to construct molecules, sometimes on the manufacturing scale, to access the new drugs.

Feb 9, 2023 | european-coatings.com | Scott France