Shelley E. Keating

Oct 7, 2024 | bmjopensem.bmj.com | Trishan Gajanand |Emily Cox |Shelley E. Keating |Wendy Brown

Aerobic exercise improves insulin sensitivity and glucose transporter type-4 expression while resistance/strength training increases muscle mass and glucose transporter type-4 expression, improving glucose uptake. Meta-analyses suggest that combined aerobic and resistance moderate-intensity continuous training (C-MICT) induces greater improvements in glycaemic control than either modality alone in people with type 2 diabetes (T2D).

Oct 1, 2024 | bmjopensem.bmj.com | Trishan Gajanand |Emily Cox |Shelley E. Keating |Wendy Brown

There were two phases for the C-HIIT and C-MICT groups (figure 1): phase 1 involved 8 weeks of supervised exercise training while phase 2 was 10 months of self-directed exercise. Those in waitlist CON continued with usual care for 8 weeks during phase 1, before being re-randomised to C-HIIT or C-MICT and completing 8 weeks of supervised training and 10 months of self-directed training.

Jun 7, 2024 | onlinelibrary.wiley.com | Daniel J. Cuthbertson |Shelley E. Keating |Patrick Owen |Graham Kemp

ALT alanine aminotransferase APRI AST to platelet ratio ASCVD atherosclerotic cardiovascular disease AST aspartate aminotransferase BMI body mass index CK-18 cytokeratin 18 CVD cardiovascular disease DXA dual-energy X-ray absorptiometry HCC hepatocellular carcinoma HDL high-density lipoprotein HOMA-IR homeostatic model assessment for insulin resistance MACE major adverse cardiovascular event MASH metabolic dysfunction-associated steatohepatitis MASLD metabolic dysfunction-associated liver...