Sherlot Juan Song

Nov 5, 2024 | cell.com | Sherlot Juan Song |Michael Berman

Keywords MASLD MASH serum markers diagnosis non-invasive multi-cohort N3-MASH Introduction Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly named non-alcoholic fatty liver disease (NAFLD), affects 25%–30% of the global population and has become the most common cause of chronic liver disease worldwide.1 About 20% of individuals with metabolic dysfunction-associated steatotic liver (MASL) progress to metabolic dysfunction-associated steatohepatitis (MASH),2 which is...

Oct 26, 2023 | onlinelibrary.wiley.com | Terry Cheuk-Fung Yip |Grace Wong |Vincent Wong |Sherlot Juan Song

Both controlled attenuation parameter (CAP) and magnetic resonance proton density fat fraction (MRI-PDFF) are validated, non-invasive methods of quantifying liver steatosis and correlate well with biopsy-proven steatosis grades.1, 2 While MRI-PDFF outperforms CAP in the accuracy of liver steatosis detection and quantification,3 its use has been limited beyond clinical trials due to cost and availability.4 Instead, CAP, a point-of-care technique for fast and reliable detection of liver...