Articles

  • Dec 8, 2024 | tandfonline.com | Justin Porter |Lacey Zimmerman |Melissa A. Nickles |Sheryl Hoyer

    AbstractBackground While IL-23 inhibitors, which include guselkumab, tildrakizumab, and risankizumab, are currently FDA-approved solely for the treatment of psoriasis, several other inflammatory skin conditions have been associated with elevated IL-23 levels. The purpose of this review is to summarize and interpret the literature surrounding the off-label uses of IL-23 inhibitors in dermatologic practice.

  • Jul 30, 2024 | mdedge.com | Jason Wei |Sheryl Hoyer

    A comprehensive metabolic panel collected from our patient 1 month earlier did not reveal any abnormalities. Serum methylmalonic acid and homocysteine were both elevated at 417 nmol/L (reference range [for those aged 2–59 years], 55–335 nmol/L) and 23 μmol/L (reference range, 5–15 μmol/L), respectively. Serum folate and 25-hydroxyvitamin D were low at 3.1 ng/mL (reference range, >4.8 ng/mL) and 5 ng/mL (reference range, 30–80 ng/mL), respectively. Vitamin B12 was within reference range.

  • Apr 10, 2024 | mdedge.com | Sheryl Hoyer |Victor Medina |Víctor Medina |Catherine Barker |Joshua Cantos

    An 83-year-old woman presented for evaluation of hyperkeratotic plaques on the medial and lateral aspects of the left heel (top). Physical examination also revealed onychodystrophy of the toenails on the halluces (bottom). A crusted friable plaque on the lower lip and white plaques with peripheral reticulation and erosions on the buccal mucosa also were present. The patient had a history of nummular eczema, stasis dermatitis, and hand dermatitis. She denied a history of cold sores.

  • Jul 16, 2023 | kevinmd.com | Sheryl Hoyer |Cindy Thompson |Linda Girgis |G. Richard Olds

    “I can’t afford higher,” Bobby’s (identifying information changed) mom explains when asked about his low dose. As Bobby’s dermatologist, I prescribed Accutane, curing 80 percent of acne with a six-month course. Insurance denied, requiring doxycycline. I rarely give antibiotics, following World Health Organization (WHO) . Antibiotics build resistance and aren’t curative, resulting in more scarring.

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