Shirley L. Zhang

Dec 6, 2024 | elifesciences.org | Yongjun Li |Nitin S. Chouhan |Shirley L. Zhang |Rebecca Moore

eLife Assessment The aim of this important study is to identify novel genes involved in sleep regulation and memory consolidation. It combines transcriptomic approaches following memory induction with measurements of sleep and memory to discover molecular pathways underlying these interlinked behaviors.

Sep 23, 2024 | biorxiv.org | Yongjun Li |Nitin S. Chouhan |Shirley L. Zhang |Rebecca Moore

AbstractMemory consolidation in Drosophila can be sleep-dependent or sleep-independent, depending on the availability of food. The anterior posterior (ap) alpha′/beta′ (α′/β′) neurons of the mushroom body (MB) are required for sleep-dependent memory consolidation in flies fed after training. These neurons are also involved in the increase of sleep after training, suggesting a coupling of sleep and memory.