Shiwen Wang

Dec 2, 2024 | nature.com | Shiwen Wang

AbstractThe antioxidant protein sulfiredoxin-1 (SRX) is an oncogenic factor that promotes tumor progression, but the regulatory mechanism underlying SRX degradation remains to be understood. Herein, we report that Keap1, the substrate-specific adapter of CRL3 complex, specifically binds and promotes the ubiquitin-mediated degradation of SRX at residue K61.

Nov 20, 2024 | onlinelibrary.wiley.com | Shiwen Wang |Engineering Beijing |Jiadong Tang |Bing Liu

Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description smll202406757-sup-0001-SuppMat.docx3.6 MB Supporting Information References 1, , , Nat. Rev. Mater. 2021, 6, 622. 2, , , , Renewable Sustainable Energy Rev. 2014, 31, 91. 3, , , , , , , Energy Environ. Sci. 2022, 15, 4148. 4, , Nature 2012, 488, 294. 5, , Nature 2012, 488, 313. 6, , Desalination 2018, 425, 156. 7, , , , , , Nat. Commun. 2020, 11, 875.

Jan 6, 2024 | mdpi.com | Shiwen Wang |Yu Wang |Ming Gao |Yifan Huang

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