Shixuan Wang

1 month ago | onlinelibrary.wiley.com | Yaosong Zhan |Shiqing Ling |Zhenya Liu |Shixuan Wang

1 Introduction The noncausal autoregressive (NAR) model has gained attention in time series modelling for its ability to capture nonlinear patterns within a stationary framework. Unlike causal models, which rely solely on lags, noncausal models incorporate both lags and leads, enabling dependence on future values. This makes them well suited to model the nonlinear and asymmetric features often observed in financial time series, such as asset price bubbles (Nyberg et al. 2012).

Jan 8, 2025 | nature.com | Shen Wang |Yang Chen |Shixuan Wang |Cong Ma

AbstractAutophagy, a conserved catabolic process implicated in a diverse array of human diseases, requires efficient fusion between autophagosomes and lysosomes to function effectively. Recently, SNAP47 has been identified as a key component of the dual-purpose SNARE complex mediating autophagosome-lysosome fusion in both bulk and selective autophagy. However, the spatiotemporal regulatory mechanisms of this SNARE complex remain unknown.

Oct 24, 2023 | nature.com | Shixuan Wang

Senescent cells (SnCs) accumulate in multiple tissue types with the process of individual aging, hindering tissue renewal and driving multiple aging-related disorders. Aside from senescence-associated secretory phenotype (SASP) neutralization and senolytics, there is an emerging senolysis strategy to eliminate SnCs by mobilizing the immunosurveillance function of cytotoxic T lymphocytes (CTLs).