Shiyao Pei

1 month ago | cell.com | Wenhua Wang |Xin Li |Rui Hu |Liang Dong |Shiyao Pei |Liping Jin | +3 more

Keywords Melanoma Tumor microenvironment T cell reprogramming BET inhibitor BCG Metallothionein 1 Introduction Cutaneous melanoma is the most aggressive skin tumor, with high mortality and poor prognosis,1 mainly associated with UV exposure and increased tumor mutation burden (TMB).2,3 Malignant melanoma is one of the most immunogenic tumors due to its higher TMB and higher potential to induce adaptive antitumor immune responses.4,5 In the past decade, immunotherapy has emerged as a powerful...