Shusen Zheng

Featured in: Favicon

nature.com Favicon

biomedcentral.com Favicon

medsci.org Favicon

genomemedicine.biomedcentral.com

Articles

FGF21 modulates immunometabolic homeostasis via the ALOX15/15-HETE axis in early liver graft injury - Nature Communications

Oct 2, 2024 | nature.com | Qiang Wei |Shusen Zheng |Di Lu

AbstractFibroblast growth factor 21 (FGF21) is essential for modulating hepatic homeostasis, but the impact of FGF21 on liver graft injury remains uncertain. Here, we show that high FGF21 levels in liver graft and serum are associated with improved graft function and survival in liver transplantation (LT) recipients.
Mitochondrial rewiring with small-molecule drug-free nanoassemblies unleashes anticancer immunity - Nature Communications

Sep 2, 2024 | nature.com | Shusen Zheng

AbstractThe immunosuppressive tumor microenvironment (TME) remains a major obstacle to tumor control and causes suboptimal responses to immune checkpoint blockade (ICB) therapy. Thus, developing feasible therapeutic strategies that trigger inflammatory responses in the TME could improve the ICB efficacy. Mitochondria play an essential role in inflammation regulation and tumor immunogenicity induction.

Contact details

Emails

[email protected]

Socials & Sites

Try JournoFinder For Free

Search and contact over 1M+ journalist profiles, browse 100M+ articles, and unlock powerful PR tools.

Start Your 7-Day Free Trial →