Siamak Amirfakhri

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Highly Selective Targeting of Pancreatic Cancer in the Liver with a Near-Infrared Anti-MUC5AC Probe in a PDOX Mouse Model: A Proof-of-Concept Study

May 20, 2023 | mdpi.com | Michael Turner |Kristin Cox |Nicholas Neel |Siamak Amirfakhri

4. DiscussionPreviously, in a PDOX model of primary pancreatic cancer (AA1305), we showed that MUC5AC-IR800 could specifically and brightly label the primary tumor and abdominal wall metastases [11]. However, the previous studies did not address the difficulties and importance of specific labeling of pancreatic cancer liver metastases, as discussed below.

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