Siberian Branch

Nov 11, 2024 | bmcpublichealth.biomedcentral.com | Siberian Branch

In this prospective cohort study, we explored the effect of alcohol consumption level on all-cause and cause-specific mortality in a Russian adult cohort followed up for over six years. To our knowledge, this is the first Russian study linking mortality register records to survey data covering both general population and in-patients treated for alcohol-related diagnoses. Our study demonstrated three times higher mortality risks in narcology patients compared to those with low-risk drinking.

May 17, 2024 | doaj.org | Siberian Branch

Updated recently 1815-3186 (Print)  / 2712-7931 (Online) Website ISSN Portal About There are no publication fees (article processing charges or APCs) to publish with this journal. Expect on average 8 weeks from submission to publication. This journal began publishing in open access in 2005. What does DOAJ define as Open Accesss? This journal uses a CC BY license.

May 12, 2024 | bmcgenomics.biomedcentral.com | Siberian Branch |George Mason

cfDNA samples of two female patients were paired-end sequenced without DNA sonication using Illumina high throuput technology. Additionally, in one of the patients, a sample of leukocyte genomic DNA was sequenced after sonication to serve as a control. To maximize coverage, whole exome plus UTR sequencing was performed instead of whole genome sequencing.

May 10, 2024 | link.springer.com | Siberian Branch

Polymorphism of genes of transforming growth factor TGFB and its receptors (TGFBRI, TGFBRII, and TGFBRIIII) in patients with primary open-angle glaucoma was analyzed. The frequency of the TGFBRII CC genotype in patients is increased relative to the control group (OR=6.10, p=0.0028). Heterozygosity in this polymorphic position is reduced (OR=0.18, p=0.0052).

May 10, 2024 | link.springer.com | Siberian Branch

We experimentally demonstrated that chronic social stress during the development of a depression-like state enhances lung metastasis and modifies the expression of many carcinogenesis- and apoptosis-related genes in the hypothalamus of mice, including genes involved in lung cancer pathogenesis in humans.