Sina Bohnacker

Dec 6, 2024 | science.org | Sina Bohnacker |Paul Baker |Huimeng Wang |Kelly Butler

Editors' ChoiceFOCIS HIGHLIGHTSKelly Butler https://orcid.org/0000-0001-6873-325X and Adam Williams https://orcid.org/0000-0002-5151-4103 Authors Info & AffiliationsAbstractLymph node IL-2 microniches guide development of TH2 cells through induction of Blimp-1 expression and an IL-10–positive feedback loop.

Dec 6, 2024 | science.org | Sina Bohnacker |Paul Baker |Huimeng Wang |Franziska Hartung

Editor’s summaryThe murine intestinal helminth parasite Heligmosomoides polygyrus bakeri (Hpb) is a key tool in understanding how helminths can suppress type 2 immune responses and facilitate chronic infection. Bohnacker et al. examined how uptake of helminthic glutamate dehydrogenase (heGDH) by macrophages suppresses immune responses.