Spartak Khutsishvili

Mar 6, 2024 | mdpi.com | Spartak Khutsishvili |Alla I. Perfileva |Natalya Lobanova |Tatyana V. Kon’kova

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May 21, 2023 | onlinelibrary.wiley.com | Satenik Mkrtchyan |Vishal Purohit |Spartak Khutsishvili |Jela Nociarová

Abstract An alternative strategy for the mechanochemical defluorinative acylation of ortho-hydroxyarylenaminones has been developed to synthesise 3-acylchromones utilizing CF3-compounds via activation of the C−F bound of the trifluoromethyl group in the presence of ytterbia (Yb2O3). The current protocol tolerated a wide range of coupling substrates to access a library of diversely substituted 3-acylchromones under the mechanochemically induced domino cyclisation mode.