Spyridon Fortis

Jul 31, 2023 | onlinelibrary.wiley.com | Spyridon Fortis |Yubo Gao |Mary Vaughan Sarrazin |Kelby Rewerts

Abstract Introduction The study objective was to estimate the prevalence of chronic hypercapnic respiratory failure (CHRF) and home noninvasive ventilation (NIV) use in a high-risk population, individuals with a history of at least one COPD-related hospitalizations. Methods We retrospectively analyzed electronic medical record data of patients with at least one COPD-related hospitalization between October 1, 2011, and September 30, 2017, to the Iowa City VA Medical Center.

May 16, 2023 | nature.com | Spyridon Fortis

AbstractIt is unclear whether the high burden of COPD in rural areas is related to worse outcomes in patients with COPD or is because the prevalence of COPD is higher in rural areas. We assessed the association of rural living with acute exacerbations of COPD (AECOPDs)-related hospitalization and mortality.

Mar 13, 2023 | atsjournals.org | Use Policies |Surya P. Bhatt |Arie Nakhmani |Spyridon Fortis

Rationale: The diagnosis of COPD is based on low ratio of the forced expiratory volume in one second to the forced vital capacity (FEV1/FVC) but its severity is classified using percentage predicted FEV1 (ppFEV1). Objective: To test a new severity classification scheme for COPD using FEV1/FVC, a more robust measure of airflow obstruction than ppFEV1. Methods: In COPDGene (n=10,132), the severity of airflow obstruction was categorized by GOLD Stages I-IV (ppFEV1 ≥80, ≥50-80, ≥30-50, and <30).