Srinivas Niranj Chandrasekaran

Dec 4, 2024 | biorxiv.org | Patrick Byrne |Srinivas Niranj Chandrasekaran |Eric Alix |John Arevalo

AbstractCell Painting images offer valuable insights into the state of a cell and enable many biological applications, but publicly available arrayed datasets only include hundreds of genes perturbed. The JUMP (Joint Undertaking in Morphological Profiling) Cell Painting Consortium perturbed roughly 75% of the protein-coding genome in human U-2 OS cells, generating a rich resource of single-cell images and extracted features.