Sriram Deivasigamani

Apr 10, 2024 | nature.com | Sriram Deivasigamani |Joshua Parrish |William J. Aronson |Christopher Kane |Martha K. Terris |Lourdes Guerrios-Rivera | +3 more

AbstractCertain widely used pathological outcome prediction models that were developed in tertiary centers tend to overpredict outcomes in the community setting; thus, the Michigan Urological-Surgery Improvement Collaborative (MUSIC) model was developed in general urology practice to address this issue. Additionally, the development of these models involved a relatively small proportion of Black men, potentially compromising the accuracy of predictions in this patient group.

Nov 24, 2023 | nature.com | Sriram Deivasigamani

AbstractProstate cancer (PCa) diagnosis relies on biopsies, with transrectal ultrasound (TRUS) biopsies being common. Fusion biopsy (FB) offers improved diagnostic accuracy, but the pain and anxiety experienced by patients during biopsies is often overlooked. This study aims to compare pain and anxiety levels between standard TRUS-guided biopsy (STB) and systematic plus MRI/US fusion biopsy (STB + FB).

Sep 4, 2023 | nature.com | Sriram Deivasigamani

There is little doubt about the effectiveness of radical prostatectomy (RP) and radiation therapy (RT) as the standard of care for prostate cancer management, particularly in intermediate and high-risk disease. In line with the “do not harm” tenet, the evolution of surgery has consistently advanced towards less invasive procedures with reduced pain and complications.