Sriram Ravichandran

Jun 5, 2024 | onlinelibrary.wiley.com | Joshua Bomsztyk |Sriram Ravichandran |Jahanzaib Khwaja |Oliver Cohen

INTRODUCTION Systemic AL amyloidosis is a condition whereby an abnormal free light chain (FLC), produced by an underlying clonal disorder, misfold and form insoluble amyloid fibrils that deposit in multiple organs resulting in progressive organ dysfunction.1 Anti-plasma cell directed therapies are employed to target the amyloid-producing clonal disorder with a view to reducing or eliminating FLC production.