Stephanie Viguers

Somerdale

Managing Editor at Healio

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healio.com

Articles

‘This is a generational change’: Why ACOG now recommends tailoring prenatal care

1 week ago | healio.com | Stephanie Viguers |Erin T. Welsh

Key takeaways: ACOG now recommends adjusting the frequency and modality of prenatal care visits based on individual risk factors. Some women may benefit from fewer in-person prenatal visits. MINNEAPOLIS — ACOG’s new guidance on transforming prenatal care in the United States took center stage at the organization’s annual conference. As Healio previously reported, the guidance recommends tailoring the frequency and modality of prenatal visits based on individual medical and social needs.
Q&A: ACOG seeks to transform century-old prenatal care approach

1 month ago | healio.com | Stephanie Viguers |Alex Friedman Peahl

Key takeaways:ACOG updated its prenatal care guidance to emphasize a more patient-centered approach. The guidance recommends that providers tailor the frequency of visits based on individual medical and social needs. ACOG recently published new prenatal guidance that recommends screening patients for social drivers of health and adjusting care based on their individual needs, including the frequency of visits and care modalities.
VIDEO: AI may help deepen understanding of obesity phenotypes

1 month ago | healio.com | Andrew Rhoades |Stephanie Viguers |Angela Fitch

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TEMPO trials: Fixed, flexible doses of tavapadon improve motor function in Parkinson’s

1 month ago | healio.com | Stephanie Viguers |Shenaz Bagha

Key takeaways: In TEMPO-1, fixed 5 mg and 15 mg doses of tavapadon improved outcomes in patients with Parkinson’s disease. TEMPO-2 showed that a flexible dose was also associated with significant improvements. SAN DIEGO — Fixed and flexible doses of tavapadon significantly improved motor function compared with placebo in patients with Parkinson’s disease, according to a pair of phase 3 trials presented at the American Academy of Neurology annual meeting.
Pridopidine beneficial in subset of patients with Huntington’s

1 month ago | healio.com | Stephanie Viguers |Shenaz Bagha

Key takeaways: Pridopidine showed promise in patients with Huntington’s disease who were not on antidopaminergic medications. The safety and tolerability of pridopidine was comparable to placebo. SAN DIEGO — Pridopidine had a positive effect on clinical progression, cognition and motor function in patients with Huntington’s disease who were not on antidopaminergic medications, according to a pre-specified analysis of the PROOF-HD trial.
Felix NeuroAI wristband improves essential tremor outcomes

1 month ago | healio.com | Stephanie Viguers

Key takeaways: An AI-powered wristband was more effective than a sham device in improving essential tremor. It could be used as an alternative for patients who have an inadequate response or cannot tolerate oral drugs. SAN DIEGO — A peripheral nerve stimulator powered by AI and worn as a wristband improved essential tremor symptoms and patients’ ability to perform daily activities compared with a sham device, data from the TRANQUIL trial show.
ACCORD-2: AXS-05 delays relapse time to Alzheimer’s disease agitation

2 months ago | healio.com | Stephanie Viguers

Key takeaways: There were no new safety signals, and treatment-emergent adverse events were comparable in the AXS-05 group and placebo group. The manufacturer is expected to apply for FDA approval in the coming months. SAN DIEGO — AXS-05 was well-tolerated and significantly delayed the time to agitation relapse compared with placebo in patients with Alzheimer’s disease, according to phase 3 data from the ACCORD-2 trial.
Nightmares may increase risk for early death

2 months ago | healio.com | Stephanie Viguers

Key takeaways: Adults who often had distressing dreams had faster biological aging and were more likely to die prematurely. The associations were independent of medication use, including antipsychotics and antidepressants. SAN DIEGO — Frequent distressing dreams may accelerate biological aging and increase the risk for early death, defined by WHO as younger than 70 years, according to a speaker at the American Academy of Neurology Annual Meeting.
Merit E. Cudkowicz, MD, MSc, receives lifetime award for ALS research: ‘I'm not done yet’

2 months ago | healio.com | Merit E. Cudkowicz |Stephanie Viguers

SAN DIEGO — At the AAN Annual Meeting, Merit E. Cudkowicz, MD, MSc, FAAN, was honored with the academy’s Lifetime Achievement Award for her extensive work in ALS research. “I have really been blessed with a great career,” Cudkowicz, executive director of the Mass General Brigham Neuroscience Institute and Julieanne Dorn Professor of Neurology at Harvard Medical School, told Healio.
Gene therapy improves motor function in spinal muscular atrophy at 52 weeks

2 months ago | healio.com | Bob Herpen |Stephanie Viguers

Key takeaways: Patients treated with onasemnogene abeparvovec recorded higher scores on all metrics vs. sham at 52 weeks. Onasemnogene abeparvovec demonstrated a favorable safety profile. Intrathecal treatment with a vector-based gene therapy was associated with a greater improvement in motor function at 52 weeks compared with sham in patients aged 2 to 18 years with spinal muscular atrophy, data show.