Stuart Oldham

Aug 6, 2024 | biorxiv.org | Ashlea Segal |Robert Smith |Sidhant Chopra |Stuart Oldham

AbstractBackground: Interindividual variability in neurobiological and clinical characteristics in mental illness is often overlooked by classical group mean case control studies. Studies using normative modelling to infer person specific deviations of grey matter volume have indicated that group means are not representative of most individuals. The extent to which this variability is present in white matter morphometry, which is integral to brain function, remains unclear.

Sep 27, 2023 | nature.com | Stuart Oldham

AbstractThe thalamus enables key sensory, motor, emotive, and cognitive processes via connections to the cortex. These projection patterns are traditionally considered to originate from discrete thalamic nuclei, however recent work showing gradients of molecular and connectivity features in the thalamus suggests the organisation of thalamocortical connections occurs along a continuous dimension.