Subhadeep Hazra

Apr 4, 2024 | pubs.rsc.org | Sourav Pramanik |Subhadeep Hazra |Ayan Chatterjee |Jaideep Saha

Hydrogen bonding-promoted tunable approach for access to aza-bicyclo-[3.3.0]octanes and cyclopenta[b] pyrroles† A unified strategy is disclosed that builds on successfully engaging the aniline nitrogen of 1,3-amphoteric γ-aminocyclopentenone for a tandem annulation with electron-poor alkynes, solely assisted by the H-bonding network of HFIP.

Jul 4, 2023 | pubs.acs.org | Biplab Mondal |Ayan Chatterjee |Subhadeep Hazra |Manveer Patel

Catalytic, reductive C–C bond formation between alkenes and vinyl cyclopropane (VCP) through hydrogen atom transfer (MHAT) is developed. Despite VCP’s use as probes in radical-clock experiments, translation of this manifold into synthetic methods for accessing elusive C–C bonds remains largely unexplored. This work represents the first foray into this front where the high chemoselectivity of MHAT for alkene over VCP was pivotal for realizing the strategy.