Suiqing Huang

Sep 16, 2023 | paperity.org | Sida Chen |Yang Huang |Suiqing Huang |Zhuoming Zhou

PLOS ONE, Jul 2023 Objective Doxorubicin (DOX) is an anthracycline antibiotic which is widely used for the treatment of various cancers, while the dose-related cardiotoxicity limits its potential therapeutic application. The underlying mechanism of DOX induced cardiotoxicity is complex and remains elusive. Our previous studies have shown that M2b macrophage plays an important role in reducing inflammation due to ischemic reperfusion injury in the myocardium.