Suzanne L. Tyas

Nov 27, 2023 | dom-pubs.onlinelibrary.wiley.com | Wajd Alkabbani |Ruth Ann Marrie |Max Rady College |Suzanne L. Tyas

1 BACKGROUND In a recent cohort study, insulin use was not associated with an increased risk of all-cause dementia after adjusting for confounding.1 The study showed how confounding by disease severity because of the lack of a clinically appropriate comparator could account for the higher risk of dementia with insulin use observed in previous observational studies.2, 3 However, questions surrounding the role of hypoglycaemia as a potential mediator of the insulin-dementia association...