Takae Kiyama

Oct 4, 2024 | digitalcommons.library.tmc.edu | Sanxiong Liu |Kimberly A Aldinger |Takae Kiyama |Mitali Dave

AbstractThe heterogeneous family of complexes comprising Polycomb repressive complex 1 (PRC1) is instrumental for establishing facultative heterochromatin that is repressive to transcription. However, two PRC1 species, ncPRC1.3 and ncPRC1.5, are known to comprise novel components, AUTS2, P300, and CK2, that convert this repressive function to that of transcription activation.