Takashi Saito Journalist Profile

Articles

Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases - Nature Communications

Aug 28, 2023 | nature.com | Erik Nutma |Nurun Fancy |Maria Weinert |Stergios Tsartsalis |Maria C. Trolese |Takashi Saito | +15 more

AbstractMicroglial activation plays central roles in neuroinflammatory and neurodegenerative diseases. Positron emission tomography (PET) targeting 18 kDa Translocator Protein (TSPO) is widely used for localising inflammation in vivo, but its quantitative interpretation remains uncertain.

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