Takayoshi Suganami

Aug 15, 2023 | frontiersin.org | Hao Cai |Durba Pal |Edward Harris |Takayoshi Suganami

Liver physiology in health and diseaseThe liver is a highly diversified organ and as such is involved in numerous key metabolic processes e.g., of lipids, proteins, complex carbohydrates, glucose and xenobiotics (1–4). Moreover, the liver plays an important role in immune regulation (5) and hemostasis. Apart from most coagulation factors (6), hepatocytes synthesize thrombopoietin (TPO), the master regulator in platelet production and maintenance (7).