Takumi Hirabayashi

Apr 16, 2024 | physoc.onlinelibrary.wiley.com | Hao Lin |Han Pan |Jihao Xing |Takumi Hirabayashi

1 INTRODUCTION Capillaries play a vital role in delivering oxygen and nutrients to skeletal muscles and are susceptible to structural alterations in response to variety of physiological circumstances (Olfert & Birot, 2011). Physical inactivity is known to cause capillary degeneration (Fujino et al., 2005). Specifically, Hindlimb-unloading (HU) are known as rodent inactivity model, can lead to capillary regression due to reduced oxygen demand (Roudier et al., 2010).