Tanguy Rieu

Jun 11, 2024 | pubs.rsc.org | Ferran Esteve |Tanguy Rieu |Jean-Marie Lehn

Key structural features to favour imines over hydrates in water: pyridoxal phosphate as a muse Imination reactions in water represent a challenge not only because of the high propensity of imines to be hydrolysed but also as a result of the competing hydrate formation through H2O addition to the aldehyde. In the present work we report a successful approach that allows for favouring imination reactions while silencing hydrate formation.

Apr 11, 2024 | pubs.rsc.org | Ferran Esteve |Tanguy Rieu |Jean-Marie Lehn

Constitutional Adaptation to pKa Modulation by Remote Ester Hydrolysis The mechanisms through which environmental conditions affect the expression of interconnected species is a key step to comprehending the principles underlying complex chemical processes. In Nature, chemical modifications triggered by the environment have a major impact on the structure and function of biomolecules and regulate different reaction pathways.