Articles

  • Mar 4, 2024 | neurologylive.com | Mark Freedman |Tanuja Chitnis |Ahmed Z. Obeidat

    March 4, 2024OpinionVideoThis program is supported by Novartis Pharmaceuticals Corporation. Content is independently developed by CMSC. Mark Freedman, MD, MSc, Tanuja Chitnis, MD, and Ahmed Obeidat, MD, PhD, discuss future directions in MS amid increasing advances in the field. Experts discuss the approach to explaining NFL results to patients and their families.

  • Jan 29, 2024 | neurologylive.com | Mark Freedman |Tanuja Chitnis |Ahmed Z. Obeidat

    Experts discuss the challenges with routine MRI usage and the potential role of serum biomarkers like neurofilament light (NFL) as an alternative. They address the correlation between serum NFL and MRI findings. Tanuja Chitnis, MD, explains that NFL levels are elevated during acute gadolinium-enhancing lesions, with variations based on lesion size and number. Larger lesions and multiple lesions correlate with higher NFL levels.

  • Jan 22, 2024 | neurologylive.com | Mark Freedman |Tanuja Chitnis |Ahmed Z. Obeidat

    January 22, 2024OpinionVideoThis program is supported by Novartis Pharmaceuticals Corporation. Content is independently developed by CMSC. Tanuja Chitnis, MD, discusses the use of ultra-sensitive assays to determine protein levels in the blood, which may aid in the diagnosis of MS. Mark Freedman, MD, MSc, addresses the historical measurement of neurofilament light chain (NFL) in spinal fluid due to higher levels, necessitating lumbar punctures.

  • Jul 19, 2023 | thelancet.com | Tanuja Chitnis

    In their Personal View in The Lancet Neurology, Andrew Solomon and colleaguesprovide a comprehensive summary of the differential diagnosis of multiple sclerosis. They aim to address the prelude to the McDonald 2017 diagnostic criteria for multiple sclerosis,which is to rule out other disorders before using the criteria.

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