Tara L. Pukala

4 weeks ago | onlinelibrary.wiley.com | Jordan L Pederick |Advanced Sensing |Akhil Kumar |Tara L. Pukala

1 INTRODUCTION Antibiotic resistance represents a significant global public health risk which is predicted to increase in prevalence if countermeasures are not implemented (World Health Organization, 2023; Murray et al., 2022). A direct route to managing antibiotic resistance is through the discovery and development of novel antibiotics.

Sep 4, 2024 | pubs.acs.org | C. Ruth Wang |Muhammad Zenaidee |Marten F. Snel |Tara L. Pukala

Sep 4, 2024 | dx.doi.org | C. Ruth Wang |Muhammad Zenaidee |Marten F. Snel |Tara L. Pukala

Oct 18, 2023 | pubs.rsc.org | Alecia R Gee |Tegan Stockdale |Molecular Biosciences |Tara L. Pukala

Efficient biocatalytic C–H bond oxidation: an engineered heme-thiolate peroxygenase from a thermostable cytochrome P450† A highly sought after reaction in chemical synthesis is the activation of unactivated carbon–hydrogen bonds. We demonstrate the hydroxylation of fatty acids using an engineered thermostable archaeal cytochrome P450 enzyme.