Tatiana Foroud

Sep 20, 2024 | nature.com | Shannon L. Risacher |Paula J Bice |Jared Brosch |Kelley Faber |Martin R Farlow |Tatiana Foroud | +29 more

AbstractDetermining the genetic architecture of Alzheimer’s disease pathologies can enhance mechanistic understanding and inform precision medicine strategies. Here, we perform a genome-wide association study of cortical tau quantified by positron emission tomography in 3046 participants from 12 independent studies. The CYP1B1-RMDN2 locus is associated with tau deposition.

Apr 6, 2023 | nature.com | Tatiana Foroud

Cite this articleReitz, C., Pericak-Vance, M.A., Foroud, T. et al. A global view of the genetic basis of Alzheimer disease. Nat Rev Neurol (2023). https://doi.org/10.1038/s41582-023-00789-zDownload citationAccepted: 21 February 2023Published: 06 April 2023DOI: https://doi.org/10.1038/s41582-023-00789-zShare this articleAnyone you share the following link with will be able to read this content:Sorry, a shareable link is not currently available for this article.