Tenzin Kunchok

Aug 18, 2024 | nature.com | Konstantine Tchourine |Keene L. Abbott |Florian Gourgue |Brian T. Do |Tenzin Kunchok |Allison Lau | +9 more

AbstractMetastases arise from subsets of cancer cells that disseminate from the primary tumour1,2. The ability of cancer cells to thrive in a new tissue site is influenced by genetic and epigenetic changes that are important for disease initiation and progression, but these factors alone do not predict if and where cancers metastasize3,4. Specific cancer types metastasize to consistent subsets of tissues, suggesting that primary tumour-associated factors influence where cancers can grow.