Thi Nhu-Y Le

Oct 17, 2024 | nature.com | Tuan Nguyen |Thi Nhu-Y Le

AbstractOur research elucidates the cleavage processes of the RNase III enzyme, DICER, which plays a crucial role in the production of small RNAs, such as microRNAs (miRNAs) and small interfering RNAs (siRNAs). Utilizing high-throughput dicing assays, we expose the bipartite pairing rule that dictates the cleavage sites of DICER.