Thomas A. Platts-Mills

2 months ago | thelancet.com | Thomas A. Platts-Mills |Lisa Workman |Martin Chapman |Jonas Lidholm

KeywordsComponent allergens from cat and miteAsthmaEarly teensIgE and IgG4 antibodiesLess abundant allergens in house dustEvidence before this studyEvidence has come from studies in Sweden, New Zealand, and the USA, that many children who live in a home with a cat become clinically tolerant to allergens derived from cats. This could occur, despite having made both sIgE and sIgG4 to the major allergen of cat (Fel d 1).

Feb 24, 2023 | cghjournal.org | Sarah McGill |Thomas A. Platts-Mills |Jana G. Hashash

DescriptionAlpha-gal syndrome is an emerging allergy first described in the early 2000s. The allergy can cause anaphylaxis, gastrointestinal (GI) symptoms, and skin changes one to several hours after ingestion of mammalian products. A GI phenotype that is increasingly recognized manifests with nonspecific symptoms like abdominal pain, diarrhea, nausea or vomiting without predominant skin, respiratory or circulatory symptoms.