Thomas E Gorochowski

Apr 29, 2024 | nature.com | Simeon D. Castle |Michiel Stock |Thomas E Gorochowski

AbstractCareful consideration of how we approach design is crucial to all areas of biotechnology. However, choosing or developing an effective design methodology is not always easy as biology, unlike most areas of engineering, is able to adapt and evolve. Here, we put forward that design and evolution follow a similar cyclic process and therefore all design methods, including traditional design, directed evolution, and even random trial and error, exist within an evolutionary design spectrum.