Thomas R. Connor

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Genomic epidemiology reveals geographical clustering of multidrug-resistant Escherichia coli ST131 associated with bacteraemia in Wales - Nature Communications

Feb 13, 2024 | nature.com | Rhys White |Mari Morgan |Brian Forde |Thomas R. Connor |Melinda M. Ashcroft

AbstractAntibiotic resistance is a significant global public health concern. Uropathogenic Escherichia coli sequence type (ST)131, a widely prevalent multidrug-resistant clone, is frequently associated with bacteraemia. This study investigates third-generation cephalosporin resistance in bloodstream infections caused by E. coli ST131. From 2013-2014 blood culture surveillance in Wales, 142 E. coli ST131 genomes were studied alongside global data.

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