Tiffany Yesavage

2 weeks ago | genengnews.com | Tiffany Yesavage

Tumor-infiltrating lymphocytes (TILs) are a grouping of mostly T cells that enter tumors and elicit an initial immune response. But as Jason Bock, PhD, co-founder and CEO of CTMC, explains, “These cells have been fighting against the tumor, but the balance has shifted, and the tumor has gained the upper hand.” He notes that traditional TIL therapy typically involves extracting the TILs from each patient’s tumor, expanding and reinvigorating them, and then reinfusing them into the patient.

2 months ago | genengnews.com | Tiffany Yesavage

Home Topics Cancer Cancer Immunotherapy: From Nineteenth-Century Beginnings to Modern Breakthroughs Hopewell delivers mRNA via lipid nanoparticles that enter the cell through endocytosis. The nanoparticle is then engulfed by the cell membrane, releasing therapeutic mRNA into the cytoplasm. [KATERYNA KON/ Science Photo Library/ Getty Images] Hopewell delivers mRNA via lipid nanoparticles that enter the cell through endocytosis.

Oct 2, 2024 | genengnews.com | Tiffany Yesavage

Home Topics Artificial Intelligence AI in Drug Design: From Hype to Real-World Results Credit: Marco Marca/ iStock / Getty Images Plus Share Facebook Twitter Linkedin ReddIt Email Experts have been raising concerns about “AI washing.” One of these experts, futurist Bernard Marr, has said that AI washing “involves exaggerating the capabilities of a product or service that is sold as ‘AI’ in order to make it look more sophisticated, innovative, or intelligent than it actually is.” This...

Jul 31, 2024 | genengnews.com | Tiffany Yesavage

Home Topics Infectious Diseases Cancer Vaccines: New Targeting Strategies, Brighter Prospects Credit: Marcin Klapczynski/iStock/Getty Images Credit: Marcin Klapczynski/iStock/Getty Images The basic idea behind cancer vaccines has been around since the 1890s, when physician William Coley administered a vaccine of sorts, a preparation of bacterial toxins, to cancer patients.

Jun 27, 2024 | biocompare.com | Tiffany Yesavage

Post-translational modifications—including phosphorylation, methylation, acetylation, ubiquitylation, and glycosylation—are covalent processes that alter the function of proteins.1 PARylation is another post-translational modification of emerging interest associated with inflammation, metabolism, and cell death.1 Although PARylation often occurs at very low levels, convenient commercial assays allow researchers to measure this phenomenon in cells.