Timothy Dobbins

Oct 7, 2023 | thelancet.com | Bette Liu |UNSW Sydney |Sandrine Stepien |Timothy Dobbins

Research in contextMany studies have estimated COVID-19 vaccine effectiveness against COVID-19 specific disease outcomes including symptomatic infection and severe disease, often measured using hospitalisations and deaths with a related SARS-CoV-2 diagnosis. Defining severe COVID-19 has become more difficult in the Omicron variant era as infection is common and misclassification of attribution can lead to uncertainty and variations in vaccine effectiveness estimates.