Toby Lawrence

Jun 4, 2024 | nature.com | Zahraa Alraies |Pablo Saez |Olivier Lamiable |Hideki Nakano |Toby Lawrence |Nicolas Manel | +1 more

AbstractImmune cells experience large cell shape changes during environmental patrolling because of the physical constraints that they encounter while migrating through tissues. These cells can adapt to such deformation events using dedicated shape-sensing pathways. However, how shape sensing affects immune cell function is mostly unknown.