Torbjorn V Ness

Aug 6, 2024 | biorxiv.org | Christof Koch |Gaute Einevoll |Torbjorn V Ness

AbstractLee et al. recently reported robust, frequency-independent subthreshold membrane coupling to extracellular current stimulation across cell classes and brain regions, in both human and mice cortical slices. Specifically, small extracellular sinusoidal electrical stimulations (ES) at frequencies between 1-140 Hz induced a local oscillation in the extracellular potential, leading to sub-threshold (< 0.5 mV) sinusoidal potentials across the cell membrane of nearby cell bodies.