Tracy Melzer

Aug 10, 2024 | nature.com | Conor Owens-Walton |Tim Anderson |Michiel F. Dirkx |Hamied Haroon |Max A. Laansma |Tracy Melzer | +12 more

AbstractThe progression of Parkinson’s disease (PD) is associated with microstructural alterations in neural pathways, contributing to both motor and cognitive decline. However, conflicting findings have emerged due to the use of heterogeneous methods in small studies. Here we performed a large diffusion MRI study in PD, integrating data from 17 cohorts worldwide, to identify stage-specific profiles of white matter differences.

Aug 10, 2024 | nature.com | Conor Owens-Walton |Tim Anderson |Michiel F. Dirkx |Hamied Haroon |Max A. Laansma |Tracy Melzer | +12 more

AbstractThe progression of Parkinson’s disease (PD) is associated with microstructural alterations in neural pathways, contributing to both motor and cognitive decline. However, conflicting findings have emerged due to the use of heterogeneous methods in small studies. Here we performed a large diffusion MRI study in PD, integrating data from 17 cohorts worldwide, to identify stage-specific profiles of white matter differences.