Tumpa Sadhukhan

Mar 24, 2023 | onlinelibrary.wiley.com | Tumpa Sadhukhan |Samya Banerjee |Dongsheng Tang |Ganghao Liang

Introduction The PtII complexes cisplatin, oxaliplatin, and carboplatin are some of the most frequently applied anticancer agents.1 Recent statistical findings have suggested that these compounds are used in more than 50 % of all chemotherapeutic treatments worldwide.2 Despite their undoubtful clinical success, the application of these metal complexes is hindered by their severe side effects (i.e., nausea, vomiting, kidney damage, and bone marrow suppression), poor tumor accumulation, and...