Ubiquitylation Unit

Sep 29, 2023 | cell.com | Ubiquitylation Unit

HighlightsTargeted protein degradation (TPD) is an exciting new modality for inducing target protein destruction in cells by harnessing cellular degradation pathways. However, to develop effective and selective degraders with clinical potential, there are many challenges, ranging from developing an effective, tissue-penetrant, and selective degrader to understanding its mode of action.

Sep 27, 2023 | cell.com | Ubiquitylation Unit

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Jun 14, 2023 | ukri.org | Ubiquitylation Unit

I have a confession to air. I spent my first decade as a scientist believing the pharmaceutical industry was evil! Much like the Orwellian conditioning of four legs good, two legs bad, I had been taught to mistrust the big pharma companies. I am now of very different mind. I am the General Manager and Deputy Head of the Medical Research Council’s (MRC) Protein Phosphorylation and Ubiquitylation Unit (PPU) at the University of Dundee.

May 4, 2023 | aacrjournals.org | Maria Alejandra |Ubiquitylation Unit

1Faculty of Biology, University of Freiburg, Freiburg, Germany. 2Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany. 3Center of Chronic Immunodeficiency (CCI) and Institute for Immunodeficiency, University Clinics and Medical Faculty, Freiburg, Germany. 4Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Freiburg, Germany. Search for other works by this author on: