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Jan 16, 2025 | 
academic.oup.com | Vagelos College
The choroid plexuses (CP) are highly vascularized structures that project into the ventricles of the vertebrate brain. The polarized epithelia of the CP produce cerebrospinal fluid by transporting water and ions into the ventricles from the blood and normally secrete a large number of proteins.
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Oct 23, 2024 | 
academic.oup.com | Vagelos College
Most prior studies of cardiovascular (CVD) events have focused on incident events. We analyzed differences by race/ethnicity in incident and recurrent CVD events in the Multi-Ethnic Study of Atherosclerosis from baseline in 2000-2002 through 2019 using joint and multivariable adjusted Cox proportional hazards modeling.
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Oct 8, 2024 | 00776-7&sz=64)
cell.com | Vagelos College |Columbia College
1Institute for Cancer Genetics, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY 10032, USA 2Herbert Irving Comprehensive Cancer Center, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY 10032, USA 3New York University School of Medicine, New York, NY 10016, USA 4Genome Damage and Stability Centre, University of Sussex, Brighton BN1 9RQ, UK 5Cancer Research Facility, Departments of Internal Medicine and Molecular Genetics & Microbiology,...
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Oct 8, 2024 | 
academic.oup.com | Vagelos College |Shirley Jackson
Type 2 diabetes (T2D) patients have reduced bone turnover and increased fractures. Advanced glycation endproducts (AGEs) impair osteoblasts and are implicated in diabetic fractures. Pyridoxamine (PM) is a vitamin B metabolite which inhibits formation of AGEs. We hypothesized that PM treatment in older T2D patients, by inhibiting AGEs, would increase bone formation. Oral PM 200 mg twice daily for one year. The primary outcome was the change in the bone formation marker P1NP.
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Sep 25, 2024 | 
academic.oup.com | Vagelos College
Accepted manuscripts are PDF versions of the author’s final manuscript, as accepted for publication by the journal but prior to copyediting or typesetting. They can be cited using the author(s), article title, journal title, year of online publication, and DOI. They will be replaced by the final typeset articles, which may therefore contain changes. The DOI will remain the same throughout.
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Sep 21, 2024 | 
academic.oup.com | Vagelos College
Once again, this year, we present highlights from the annual meeting of the American Society of Clinical Oncology, held in Chicago, with over 40,000 attendees and over 5,000 oral and poster presentations. A large number of studies were interesting for a variety of reasons, so of course we had to be selective in what we could include and share below with the readership of The Oncologist. The abstracts can be accessed at ASCO.org.
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Jul 11, 2024 | 
academic.oup.com | Vagelos College
Atrial fibrillation (AF) is a prevalent cardiac condition characterized by irregular heart rhythm. Traditional non-invasive diagnostic tools, while useful, have limitations in providing comprehensive information for treatment planning. To address this gap, Electromechanical Cycle Length Mapping (ECLM), a noninvasive echocardiography-based technique, has emerged as a promising approach.
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Jul 3, 2024 | 
academic.oup.com | Vagelos College
We explored state-level indicators of structural racism on internalizing symptoms of depressive affect among US adolescents. We merged 16 indicators of state-level structural racism with 2015-19 Monitoring the Future surveys (N=41,258) examining associations with loneliness, self-esteem, self-derogation, and depressive symptoms using regression analyses.
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Jun 11, 2024 | 
karger.com | Vagelos College
Introduction: Sleep disturbances have been associated with essential tremor (ET). However, their pathophysiological underpinnings remain unknown. In this exploratory study, we examined the association between subjective sleep disturbances and the presence of Lewy pathology (LP) on postmortem brain examination in ET cases. Methods: Fifty-two ET cases enrolled in a prospective, longitudinal study were assessed over an average period of 42 months.
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Apr 24, 2024 | 
diabetesjournals.org | Vagelos College
OBJECTIVEWe examined the association of arsenic in federally regulated community water systems (CWS) and unregulated private wells with type 2 diabetes (T2D) incidence in the Strong Heart Family Study (SHFS), a prospective study of American Indian communities, and the Multi-Ethnic Study of Atherosclerosis (MESA), a prospective study of racially and ethnically diverse urban U.S. communities.
