Valerio Carelli

2 months ago | digitalcommons.library.tmc.edu | Amel Karaa |Enrico Bertini |Valerio Carelli |Bruce Cohen

BACKGROUND: As previously published, the MMPOWER-3 clinical trial did not demonstrate a significant benefit of elamipretide treatment in a genotypically diverse population of adults with primary mitochondrial myopathy (PMM).

Jul 19, 2024 | digitalcommons.library.tmc.edu | Amel Karaa |Enrico Bertini |Valerio Carelli |Bruce Cohen

BACKGROUND AND OBJECTIVES: Primary mitochondrial myopathies (PMMs) encompass a group of genetic disorders that impair mitochondrial oxidative phosphorylation, adversely affecting physical function, exercise capacity, and quality of life (QoL). Current PMM standards of care address symptoms, with limited clinical impact, constituting a significant therapeutic unmet need.

Jun 2, 2023 | n.neurology.org | Amel Karaa |Enrico Bertini |Valerio Carelli |Bruce Cohen

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