van Laar

Dec 4, 2024 | academic.oup.com | van Dijk |van Laar |de Vries-Bouwstra

Cellular senescence and endothelial-to-mesenchymal transition (EndMT) are profibrotic cellular processes involved in systemic sclerosis (SSc), but how they respond to treatment is largely unknown.

Oct 9, 2024 | academic.oup.com | van Laar

Difficult-to-treat rheumatoid arthritis (D2T RA) is an area of high unmet need. The prevalence reported in the first D2T RA cohort studies ranged from 5.5–27.5%. Key to the definition is a conviction by patient and/or rheumatologist that disease management has become problematic and failure of at least two biological or targeted synthetic disease-modifying antirheumatic drugs.

Oct 31, 2023 | zenodo.org | van Laar

SummaryThis submission contains a reconstruction from a tomographic dataset and a structured light scan of a small wooden block. The data is made available as part of [Bossema et al., 2023] and is meant to serve as a practice dataset for the Blender plugin that is published along the article. The code for the plugin can be found here and on github.

Sep 13, 2023 | paperity.org | van Laar

Journal of Neural Transmission, Jul 2023 This article provides an overview of the various screening and selection tools which have been developed over the past 25 years to identify patients with Parkinson’s disease (PD) possibly eligible for device-aided therapies (DATs). For the available screening tools, we describe the target therapies (subtypes of DAT), development methods, validation data, and their use in clinical practice.