Vanessa Borgmann

Feb 7, 2024 | onlinelibrary.wiley.com | Franziska Otto |Antonio Vogelsberg |Lennart Harland |Vanessa Borgmann

Follicular helper T-cell lymphoma, angioimmunoblastic type (AITL) is one of the most prevalent types of peripheral T-cell lymphoma (PTCL).1 It is often accompanied by secondary, commonly EBV-positive B-cell lymphoproliferations (LPDs), which are thought to be facilitated in part by a paraneoplastic dysregulation of the immune system.2 Genetically, AITL is characterized by recurrent alterations in the epigenetic regulators DNMT3A, TET2 and IDH2, as well as in the GTPase RHOA.3 Recent studies...