Vengadesh Letchumanan

Apr 26, 2023 | frontiersin.org | van Beek |von Georg |Vengadesh Letchumanan |Angelo V. Marzano

IntroductionBullous pemphigoid (BP) is the most common autoimmune blistering disorder in Europe, with an incidence of 0.0419 per 1000 person-years, which is increasing by time, and typically develops in individuals over the age of 70 years (1–5). It occurs when autoantibodies target the hemidesmosomal proteins BP180 (type XVII collagen) and/or BP230 in the epidermal basement zone (1, 6, 7).