Verdon Taylor

Jun 5, 2023 | frontiersin.org | Verdon Taylor

Aikaterini Lampada1 and Verdon Taylor1* 1Department of Biomedicine, University of Basel, Switzerland The final, formatted version of the article will be published soon. Receive an email when it is updated Neurogenesis ceases in most regions of the mammalian brain before or shortly after birth, however, in a few restricted brain regions, the production of new neurons proceeds into adulthood.

Apr 12, 2023 | nature.com | Vinod Udayar |Martino L. Morella |Verdon Taylor |David J. Vocadlo |Alexandra Gehrlein |Martin Ebeling

AbstractMutations in glucocerebrosidase cause the lysosomal storage disorder Gaucher’s disease and are the most common risk factor for Parkinson’s disease. Therapies to restore the enzyme’s function in the brain hold great promise for treating the neurological implications. Thus, we developed blood-brain barrier penetrant therapeutic molecules by fusing transferrin receptor-binding moieties to β-glucocerebrosidase (referred to as GCase-BS).