Victoria Hansen

Sep 22, 2023 | biorxiv.org | Victoria Hansen |Ryan Gray |Fangzhou Bian |Yanshi Chen

AbstractThe growth plate is essential for maintaining skeletal growth; however, the mechanisms governing postnatal growth plate homeostasis are poorly understood. Here we show that ADGRG6/GPR126, a cartilage-enriched G protein-coupled receptor (GPCR), is dispensable for embryonic limb development but is required for postnatal growth plate homeostasis.